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They are primarily generated through enzymatic reactions involving NADPH oxidases (NOXs), cytochrome P450 reductase (POR), and NADH-cytochrome b5 reductase (CYB5R1), with the mitochondrial electron transport chain (mETC) serving as another significant source (Yan et al., 2021)
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418,419,420 MASLD The diagnosis of MASLD is based on three criteria: (1) imaging diagnosis of hepatic steatosis and/or liver biopsy findings of ≥ 5% hepatocyte ballooning degeneration
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